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People who suffer from major depressive disorder worldwide, about 1/3 of them don’t respond to currently available treatments. This represents a major unmet public health need,” said Mathai Mammen, MD, Ph.D., Global Head, Janssen Research & Development, LLC, in a statement.
Esketamine nasal spray DNA was supported by data from 5 phases. 3 studies in patients with treatment-resistant depression. Patients with treatment-resistant depression are those whose depression has not responded to 2 or more treatments. Buy Esketamine online at our online drugstore with super fast safe and secure delivery.
The most commonly reported treatment-related adverse effects (>10%) in the Esketamine treatment group were metallic taste, nausea, vertigo, dizziness, headache, drowsiness, dissociation, blurred vision, paranesthesia, and anxiety. While in the placebo group, metallic taste and headache were reported.
Also, this drug was proven to target critical aspects of glutamate-mediated synaptic plasticity. Thereby bringing about rapid and sustained improvement in people with treatment-resistant depression, ” said Husseini K. Manji, MD, Global Head, Neuroscience Therapeutic Area, Janssen Research & Development, LLC.
The FDA previously granted ketamine nasal spray a Breakthrough Therapy Designation for use in treatment-resistant depression. And also for a second indication, major depressive disorder with imminent risk for suicide.
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